Ranked guide · Knoxville, Tennessee
The 10 Best Med Spas in Knoxville (2026)
The top-rated aesthetic clinics and med spas in Knoxville, ranked by real Google ratings and review volume. Every listing links to the clinic's full profile so you can compare treatments, pricing, and book a free consultation.
- 1
Southeastern Dermatology
Knoxville, Tennessee
Southeastern Dermatology holds a 4.9★ rating across 1,082 Google reviews. It offers 24 treatment categories in Knoxville.
- 2
Meridiem DermSpa - Farragut
Knoxville, Tennessee
Meridiem DermSpa - Farragut holds a 4.9★ rating across 1,063 Google reviews. It offers 18 treatment categories in Knoxville.
- 3
Pretty Girl Aesthetics
Knoxville, Tennessee
Pretty Girl Aesthetics holds a 4.9★ rating across 967 Google reviews, based in Knoxville. It offers 30 treatment categories in Knoxville.
- 4
Refine Dermatology
Knoxville, Tennessee
Refine Dermatology holds a 4.9★ rating across 903 Google reviews. It offers 11 treatment categories in Knoxville.
- 5
Dolce Medical Spa
Knoxville, Tennessee
Dolce Medical Spa holds a 4.9★ rating across 872 Google reviews, based in Knoxville. It offers 20 treatment categories in Knoxville.
- 6
Beautique Medical Anti-Aging
Knoxville, Tennessee
Beautique Medical Anti-Aging holds a 5★ rating across 544 Google reviews, based in Knoxville. It offers 40 treatment categories in Knoxville.
- 7
Smiley Aesthetics Medical Spa – Botox & Weight Loss Clinic Knoxville
Knoxville, Tennessee
Smiley Aesthetics Medical Spa – Botox & Weight Loss Clinic Knoxville holds a 5★ rating across 529 Google reviews, based in Knoxville. It offers 26 treatment categories in Knoxville.
- 8
The Wellness Room
Knoxville, Tennessee
The Wellness Room holds a 5★ rating across 528 Google reviews, based in Knoxville. It offers 31 treatment categories in Knoxville.
- 9
Knoxville Glow Medical Weight Loss, Wellness & Aesthetics
Powell, Tennessee
Knoxville Glow Medical Weight Loss, Wellness & Aesthetics holds a 4.9★ rating across 671 Google reviews, based in Powell. It offers 16 treatment categories in Knoxville.
- 10
RevitalyzeMD
Knoxville, Tennessee
RevitalyzeMD holds a 4.9★ rating across 654 Google reviews, based in Knoxville. It offers 35 treatment categories in Knoxville.
See the full directory of med spas in Knoxville, or read our guide on how to choose a med spa.
Where Knoxville's clinics are

Best med spas in Knoxville: common questions
What is the best med spa in Knoxville?
By Google rating and review volume, Southeastern Dermatology (4.9★ across 1,082 reviews) ranks at the top of our Knoxville list for 2026. The "best" choice ultimately depends on the specific treatment you want and your neighborhood. Compare the full ranked list above and request consultations from your top two or three picks.
How did you rank the best med spas in Knoxville?
We rank clinics by their public Google rating, weighted by how many reviews back it. Every clinic starts from the same baseline score and its rating counts for more as its review count grows, so a strong rating held across many hundreds of reviews ranks above a perfect rating from a short record. Ratings and review counts reflect public Google data as of 2026; always confirm current details directly with each clinic. This list is editorial and is not influenced by payment.
How much do treatments cost at Knoxville med spas?
It depends on the treatment: injectables like Botox are priced per unit or area, while body and laser treatments are priced per session or package. See local cost ranges on each treatment page, and our cost guides for full breakdowns. Most Knoxville clinics offer free consultations to give you an exact quote.
How do I choose the right med spa in Knoxville?
Look for licensed, experienced providers (physician oversight for injectables and lasers), transparent pricing, real before-and-after photos, and strong, recent reviews. Our guide on how to choose a med spa walks through the exact questions to ask before you book.